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●Purchase●DescriptionEpacadostat(INCB024360)isanorallyavailablehydroxyamidineandinhibitorofindoleamine2,3-dioxygenase(IDO1),withanIC50of10nM
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Epacadostat (INCB024360) is an orally available hydroxyamidine and inhibitor of indoleamine 2,3- dioxygenase (IDO1), with an IC50 of 10 nM. It shows little activity against other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). Epacadostat displays potential immunomodulating and antineoplastic activities.
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